Botox Cosmetic

What is botox cosmetic?

The treatment that uses the botulinum toxin in its purified form for reducing the appearance of wrinkles is known as botox cosmetic. As we age, the skin starts to lose its firmness and elasticity. As the aging process continues fine lines and wrinkles become noticeable resulting in skin folds and creases.

Frown lines between the eyebrows can make you look angry, tired or unhappy; in such cases Botox cosmetic is very useful. Botox treatment has been used by doctors for many years. It helps in reducing wrinkles by plumping up the tissues and decreases the activity of facial muscles that produce the wrinkles. To get rid of aging lines or eliminate skin wrinkles and fine lines on your facial skin the Botox is used in the form of injection. It only a few minutes to inject by a skilled provider. Botox cosmetic is a simple procedure performed on an office visit. Botox cosmetic reduces the appearance of fine lines and wrinkles giving a natural appearance. Botox cosmetic administered properly by a skilled provider is safe and effective.

During Botox cosmetic treatment, you may slightly feel discomfort due to tiny needles. This discomfort will disappear after treatment is completed. After Botox cosmetic treatment,  the muscles are relaxed and the wrinkle becomes smooth giving you fresh, young and glowing look on skin with full effect expressed at 14 days.

How Do Botox injections work?

Botox Cosmetic is an injectable that reduces the appearance of fine lines and wrinkles. The bacterium Clostridium botulinum has powerful muscle relaxing abilities.

Botox cosmetic contains a substance that works underneath the skin’s surface. Botox inhibits the signals from the nerves to the muscles. The injected muscle cannot contract. This causes fine lines and wrinkles to be reduced. Botox is frequently utilized on forehead lines, crow’s feet (lines around the eye), and frown lines. The sun and gravity can cause wrinkles. Botox is not a filler.

Botox Cosmetic is injected with a fine needle into specific muscles with minor ease. Botox cosmetic generally takes 7 to 14 days to express full results. You should abstain from alcohol one to two weeks before the procedure. You should avoid NSAIDs 7-10 days prior to the procedure.

Is Botox painful?

Topical analgesics can be applied prior to Botox treatment to make the procedure more comfortable. Without topical analgesics, the discomfort is minimal with a Botox treatment.

Every Botox session is comprised of a few little injections of botulinum toxin type A. The amount of Botox is dictated by the area that is to be injected. Some areas require more Botox than others. The level of discomfort is dependent upon patient’s pain tolerance.

The injection treatment itself will take 10 minutes and can even be booked into your lunch hour easily with little to no downtime. After a quick session, it is possible to return to the daily hustle of work, family, and life, confident in the knowledge that you have cared for yourself with a little well-deserved pampering.

How Long Does Botox Injection Last?

Botox Cosmetic is an injectable toxin that will reduce the appearance of fine lines and wrinkles. In general, Botox injections can last from 3 to 6 months from one treatment. Depending on the patient’s individual activity, Botox can be metabolized at different rates shortening or lengthening its effects. Botox has many medical uses, like treating migraines, reducing neck spasms and reducing contractures.

Different factors will affect how long Botox cosmetic would last including:

• your age
• the elasticity of your skin
• wrinkle depth
• other factors

For example, if you’re using botulinum toxin to reduce the appearance of deep wrinkles, the wrinkles will not fully disappear. The effects can also wear off quicker.

How often should you get Botox injections?

While botulinum toxin will quickly block nerve communication, the results are not permanent. As the effects of Botox cosmetic wear off, you’ll begin to notice the fine lines and wrinkles returning. However, with regular treatment, these fine lines and wrinkles can diminish.

Botox treatment is administered in units of Botox. Therefore, if less Botox is injected into an area which requires more units of Botox; results and effect diminish quicker. During your visit to a skilled provider, he or she will determine the amount of units required for each area.

Are there any risks or side effects?

Botox cosmetic injections are relatively safe. Minor side effects are possible, for example, pain at the injection site, infection, inflammation, and swelling, redness, bleeding and bruising.

Symptoms that indicate an allergic reaction are itching, wheezing, asthma, a rash, red welts, dizziness and faintness. Dry mouth, fatigue, headache and neck pain have been reported. Let your doctor know immediately if you have any breathing issues or a faint or dizzy feeling.

Who Should Not Receive Botox? Or Are you a good candidate for Botox?

Botox Cosmetic has been approved by the United States FDA for people aged 18 to 65. But, avoid using it if you are allergic to any ingredients in Botox or Botox Cosmetic.

• Have a skin problem or other condition to the applying area
• Any disease that can affect your muscles or nerves like ALS (Lou Gehrig’s disease), myasthenia gravis, Eaton-Lambert syndrome
• Have breathing problems, such as asthma
• Have difficulty in swallowing
• Have bleeding issues
• Plan to undergo surgery
• Have had facial surgery
• Have weakness in your forehead muscles
• Have drooping eyelids
• If you are planning or trying to conceive a child, are pregnant, are planning to breastfeed or are currently breastfeeding. It’s better to be safe, and you can always have Botox at a later date

Indications, Important Safety Information, and Prescribing Information

BOTOX® Cosmetic (onabotulinumtoxinA) Important Information

Indications

BOTOX® Cosmetic (onabotulinumtoxinA) is indicated in adult patients for the temporary improvement in the appearance of:

– Moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity

– Moderate to severe lateral canthal lines associated with orbicularis oculi activity

– Moderate to severe forehead lines associated with frontalis activity

IMPORTANT SAFETY INFORMATION, INCLUDING BOXED WARNING

WARNING: DISTANT SPREAD OF TOXIN EFFECT

Postmarketing reports indicate that the effects of BOTOX® Cosmetic and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These may include asthenia, generalized muscle weakness, diplopia, ptosis, dysphagia, dysphonia, dysarthria, urinary incontinence, and breathing difficulties. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity, but symptoms can also occur in adults treated for spasticity and other conditions, particularly in those patients who have an underlying condition that would predispose them to these symptoms. In unapproved uses and approved indications, cases of spread of effect have been reported at doses comparable to those used to treat cervical dystonia and spasticity and at lower doses.

CONTRAINDICATIONS

BOTOX® Cosmetic is contraindicated in the presence of infection at the proposed injection site(s) and in individuals with known hypersensitivity to any botulinum toxin preparation or to any of the components in the formulation.

WARNINGS AND PRECAUTIONS

Lack of Interchangeability Between Botulinum Toxin Products

The potency units of BOTOX® Cosmetic are specific to the preparation and assay method utilized. They are not interchangeable with other preparations of botulinum toxin products and, therefore, units of biological activity of BOTOX® Cosmetic cannot be compared to nor converted into units of any other botulinum toxin products assessed with any other specific assay method.

Spread of Toxin Effect

Please refer to Boxed Warning for Distant Spread of Toxin Effect.

No definitive serious adverse event reports of distant spread of toxin effect associated with dermatologic use of BOTOX® Cosmetic at the labeled dose of 20 Units (for glabellar lines), 24 Units (for lateral canthal lines), 40 Units (for forehead lines with glabellar lines), 44 Units (for simultaneous treatment of lateral canthal lines and glabellar lines), and 64 Units (for simultaneous treatment of lateral canthal lines, glabellar lines, and forehead lines) have been reported. Patients or caregivers should be advised to seek immediate medical care if swallowing, speech, or respiratory disorders occur.

Serious Adverse Reactions With Unapproved Use

Serious adverse reactions, including excessive weakness, dysphagia, and aspiration pneumonia, with some adverse reactions associated with fatal outcomes, have been reported in patients who received BOTOX® injections for unapproved uses. In these cases, the adverse reactions were not necessarily related to distant spread of toxin, but may have resulted from the administration of BOTOX® to the site of injection and/or adjacent structures. In several of the cases, patients had pre-existing dysphagia or other significant disabilities. There is insufficient information to identify factors associated with an increased risk for adverse reactions associated with the unapproved uses of BOTOX®. The safety and effectiveness of BOTOX® for unapproved uses have not been established.

Hypersensitivity Reactions

Serious and/or immediate hypersensitivity reactions have been reported. These reactions include anaphylaxis, serum sickness, urticaria, soft-tissue edema, and dyspnea. If such reactions occur, further injection of BOTOX® Cosmetic should be discontinued and appropriate medical therapy immediately instituted. One fatal case of anaphylaxis has been reported in which lidocaine was used as the diluent and, consequently, the causal agent cannot be reliably determined.

Cardiovascular System

There have been reports following administration of BOTOX® of adverse events involving the cardiovascular system, including arrhythmia and myocardial infarction, some with fatal outcomes. Some of these patients had risk factors including pre-existing cardiovascular disease. Use caution when administering to patients with pre-existing cardiovascular disease.

Increased Risk of Clinically Significant Effects With Pre-existing Neuromuscular Disorders

Individuals with peripheral motor neuropathic diseases, amyotrophic lateral sclerosis, or neuromuscular junction disorders (eg, myasthenia gravis or Lambert-Eaton syndrome) should be monitored when given botulinum toxin. Patients with neuromuscular disorders may be at increased risk of clinically significant effects including generalized muscle weakness, diplopia, ptosis, dysphonia, dysarthria, severe dysphagia, and respiratory compromise from onabotulinumtoxinA (see Warnings and Precautions).

Dysphagia and Breathing Difficulties

Treatment with BOTOX® and other botulinum toxin products can result in swallowing or breathing difficulties. Patients with pre-existing swallowing or breathing difficulties may be more susceptible to these complications. In most cases, this is a consequence of weakening of muscles in the area of injection that are involved in breathing or oropharyngeal muscles that control swallowing or breathing (see Boxed Warning).

Pre-existing Conditions at the Injection Site

Caution should be used when BOTOX® Cosmetic treatment is used in the presence of inflammation at the proposed injection site(s) or when excessive weakness or atrophy is present in the target muscle(s).

Dry Eye in Patients Treated With BOTOX® Cosmetic

There have been reports of dry eye associated with BOTOX® Cosmetic injection in or near the orbicularis oculi muscle. If symptoms of dry eye (eg, eye irritation, photophobia, or visual changes) persist, consider referring patients to an ophthalmologist.

Human Albumin and Transmission of Viral Diseases

This product contains albumin, a derivative of human blood. Based on effective donor screening and product manufacturing processes, it carries an extremely remote risk for transmission of viral diseases and variant Creutzfeldt-Jakob disease (vCJD). There is a theoretical risk for transmission of Creutzfeldt-Jakob disease (CJD), but if that risk actually exists, the risk of transmission would also be considered extremely remote. No cases of transmission of viral diseases, CJD or vCJD have ever been identified for licensed albumin or albumin contained in other licensed products.

ADVERSE REACTIONS

The most frequently reported adverse reactions following injection of BOTOX® Cosmetic for glabellar lines were eyelid ptosis (3%), facial pain (1%), facial paresis (1%), and muscular weakness (1%).

The most frequently reported adverse reaction following injection of BOTOX® Cosmetic for lateral canthal lines was eyelid edema (1%).

The most frequently reported adverse reactions following injection of BOTOX® Cosmetic for forehead lines with glabellar lines were headache (9%), brow ptosis (2%), and eyelid ptosis (2%).

DRUG INTERACTIONS

Co-administration of BOTOX® Cosmetic and aminoglycosides or other agents interfering with neuromuscular transmission (eg, curare-like compounds) should only be performed with caution as the effect of the toxin may be potentiated. Use of anticholinergic drugs after administration of BOTOX® Cosmetic may potentiate systemic anticholinergic effects.

The effect of administering different botulinum neurotoxin products at the same time or within several months of each other is unknown. Excessive neuromuscular weakness may be exacerbated by administration of another botulinum toxin prior to the resolution of the effects of a previously administered botulinum toxin.

Excessive weakness may also be exaggerated by administration of a muscle relaxant before or after administration of BOTOX® Cosmetic.

USE IN SPECIFIC POPULATIONS

There are no studies or adequate data from postmarketing surveillance on the developmental risk associated with use of BOTOX® Cosmetic in pregnant women. There are no data on the presence of BOTOX® Cosmetic in human or animal milk, the effects on the breastfed child, or the effects on milk production.

Please see BOTOX® Cosmetic full Prescribing Information including Boxed Warning and Medication Guide.